CogniFactors

Enhanced mental clarity, improved memory retention and improved attention are benefits of continued use of CogniFactors.

N-Acetyl L-Carnitine (ALCAR): normally produced in the mitochondria, is a precursor of acetyl-Coenzyme A in the tricarboxylic acid (TCA) cycle. ALCARs ability to attenuate oxidative stress and mitochondrial prevent ATP depletion is why ALCAR is considered a neuronal support compound. ALCAR protects against beta-amyloid neurotoxicity. ALCAR significantly reduces oxidative damage to RNA. Electron microscope studies of the hippocampus of old rats showed that ALCAR and or R-Alpha Lipoic acid reversed age-associated mitochondrial structural decay.

Phosphatidylserine (PS): enhances cholinergic function, restores Acetylcholine release (in aging rats) and prevents agerelated reduction in dendritric spine density in the rat hippocampus. Studies have shown PS to restore Protein Kinase C activity. PS has demonstrated some usefulness in treating cognitive impairment, age-associated memory impairment and is useful in treating those patients with the more well known degenerative memory impairment conditions.

Dimethyl Amino Ethinol (DMAE): is made naturally in the brain. It has been shown to alleviate behavioral problems and normalize activity levels and attention. DMAE increases attention span, decreases aggressive behavior, improves learning ability and occasionally shows an increase in IQ (70% of those with deficient attention span). DMAE inhibits and reverses crosslinking of proteins. Removal of age spots (lipofuscin pigment) from skin and neurons is enhanced. Anxiety is reduced and alertness is enhanced. Motivation is enhanced and apathy is reduced. DMAE improves interhemispheric flow of information in the corpus callosum thereby improving creativity and verbal fluency. Sleep need is reduced by ~ 1 hour after 6 weeks of use. Dreams become more vivid and sleep is sounder and more refreshing. DMAE enhances Acetylcholine, Choline and RNA levels within the brain. DMAE has a superior ability to cross the Blood-Brain-Barrier.

Ginkgo Biloba extract (GBE): is widely used as a dietary supplement for increasing cognitive function in elderly people. Its action is through its enhanced circulation (vasodilation) effects and through its neuroprotective antioxidant qualities. Quality of GBE varies widely. In 1999 consumer labs showed that nearly 25% of GBE brands tested did not meet their label claims of expected chemical marker compounds despite claims to being standardized.

Vinpocetine: increases cerebral blood flow and metabolism. Vinpocetine comes from the plant Vinca minor and has a long standing use as an aide to cognitive enhancement. Studies confirm its neuroprotective and antioxidant properties. Vinpocetine may have anticonvulsant benefits.

Alpha R Lipoic Acid: has strong antioxidant protective qualities and enhances antioxidant recycling. ARLA also supports enhanced mitochondrial metabolism through its support of the Krebs Citric Acid cycle and ATP production. This antioxidant is both fat and water soluble. ARLA may slow brain aging and have antiaging benefits. ARLA has neuroprotective benefits. ARLA is the biologically active form of lipoic acid and as such is considerably stronger than synthetic ALA (alpha RS Lipoic Acid, racemic mixture).

Huperzine A: from the moss Huperzia serrata, is a potent neuroprotective agent. Huperzine A gives support for healthy cognitive function. Balancing Glutamatergic function protects against Glutamate toxicity. Huperzine A prevents breakdown of acetylcholine by inhibiting acetylcholinesterase enzyme activity.